UC Merced

Objective: Adding to the literature on the development and evaluation of interventions to increase HPV vaccination intentions and uptake in adults, the current project outlines the development and evaluation of a theoretically-guided health communication video containing information on HPV, the HPV vaccine, and HPV-related cancers. This project also examines the feasibility of the intervention and evaluates with a pilot randomized controlled trial (RCT), the efficacy of the newly designed health communication video compared to an attentional control condition and the standard-of-care condition in increasing the intentions of the HPV vaccine in an adult, college population. Methods: Two studies were conducted: (1) a mixed-methods approach to the development and evaluation of a CSM-guided narrative video, and (2) a pilot, RCT that examined the feasibility and efficacy of the newly developed narrative video. Study 1 was conducted in three phases: Phase 1: Script Content Development, Phase 2: Script Content Evaluation and Refinement, and Phase 3: Video Evaluation and Refinement. For study 3, university undergraduate students (N = 72) were randomized to either the narrative intervention condition (n = 25), an attentional control condition (n = 24), or a standard-of-care condition (n = 23). Participants completed a baseline survey and two days post-baseline they completed the intervention condition and post-intervention survey. Participants also completed a one-month follow-up survey. Results: Study 1 results indicate the newly developed narrative video was appealing, persuasive, interesting, believable, of high quality, and provided new information about HPV and the HPV vaccine. Study 2 results indicate that it is feasible to recruit participants to complete an intervention to increase HPV vaccine intentions and uptake in a Hispanic-majority university population. Further, the pilot RCT findings reflected the expected patterns of correlations and mean differences of survey measures over time. Conclusions: This project successfully developed and evaluated a theoretically-guided health communication video for college students containing information on HPV, the HPV vaccine, and HPV-related cancers. The feasibility and pilot RCT indicate the expected patterns of findings for primary and secondary outcome measures. A full RCT will be conducted that will be powered to detect meaningful differences among intervention conditions.